GLP-1 Agonists Are Still Going Strong
Consumers are flooded with weight loss options—from exercise apps to intermittent fasting to ketogenic diets. But nothing is making waves like GLP-1s.
GLP-1 agonists, such as Ozempic and Wegovy, are transforming weight management. The results are impressive—but they don’t come without challenges.
Digestive Challenges with GLP-1 Agonists
Up to 70% of GLP-1 users struggle with GI discomfort, including nausea, vomiting and diarrhea. Meanwhile, 86% fail to meet protein needs, risking muscle loss, slowed metabolism, and fatigue.
The result? Poor adherence, consumer dropout and stalled outcomes. For formulators, this presents a significant opportunity to provide solutions that help consumers stay on track.
GLP-1 Market Size
Today, roughly six percent of U.S. adults use GLP-1 drugs, another 12% have tried them and nearly 1/3 are aware of them.
It’s no surprise that by 2035, the GLP-1 market is projected to triple in size—jumping from $4.1 billion to $13 billion.
As millions of consumers embrace GLP-1s, the need for support solutions that keep them comfortable, nourished and on track will skyrocket.
Enter the DigeSEB® line.

The Gold Standard in Digestive Enzymes
For more than three decades, DigeSEB® has set the gold standard in digestive support. The DigeSEB® line is expertly formulated to support optimal digestion and nutrient absorption, helping consumers digest food properly and avoid discomfort.
It’s the foundation every GLP-1 companion product needs.
- Relief from gas, bloating & abdominal discomfort
- Healthy bowel movements & regularity
- Management of indigestion
- Efficient nutrient absorption
- Digestion of fats, carbs, dairy & proteins
- Release of nutrients trapped in difficult-to-digest plant cell walls
- Breakdown of raffinose family oligosaccharides (RFOs)
Clean-label, Non-GMO Project verified, Halal and Kosher-certified, DigeSEB® supports consumers in remaining comfortable and nourished.
Specific Challenges. Targeted Solutions.
DigeSEB Super™
Next-Level Digestive Support
| When food intake drops and digestion slows, every bite counts. DigeSEB Super™ is expertly formulated to help consumers extract maximum nutrition without GI discomfort.
A recently published study showed DigeSEB Super™ increased the release of sugars, amino acids and free fatty acids by up to 69% within one hour, demonstrating improved digestion of carbohydrates, proteins and fats. |
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It’s the next-level digestive support consumers need to feel better and stick with GLP-1s.
DigeSEB Sport™
Support Muscle. Fuel Energy.
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Consumers on GLP-1s often fall short on protein, risking muscle loss and fatigue. DigeSEB Sport™ is specifically designed to help them get the most out of every gram of protein.
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DigeSEB Sport™ is the perfect add-on to protein and sports nutrition products, helping consumers stay strong, energized and engaged during and after their GLP-1 journey.
The Bottom Line
GLP-1 therapy is a breakthrough, but it isn’t a silver bullet. Without support, consumers face real risks: GI discomfort, nutrient gaps and muscle loss.
Formulators who incorporate DigeSEB Super™ and DigeSEB Sport™
can deliver the targeted, research-backed support that consumers need.
The payoff is simple: happier, healthier consumers who stay the course—and products that win in a rapidly expanding market.
The GLP-1 era is here. Ensure your products rise to meet the challenge with the DigeSEB Super™ and DigeSEB Sport™.
Let’s Connect at Supplyside Global
Our team of enzyme and probiotic experts is looking forward to meeting you at SupplySide Global. Schedule a meeting in advance or stop by Booth #3465 during the show, October 27-30. Let’s discuss how our science-backed branded ingredients can make your formulations shine!
SOURCES
- GLP-1 side effects only one factor driving patient discontinuation rates. BioSpace. (2025, March 10).
- Enhancing GLP-1 benefits with protein intake. PURIS. (2025, February 11).
- Future Market Insights. (2025, July 16). GLP-1 nutritional support market size & share 2025-2035. Future Market Insights.
- Rathi, A., Potale, S., Vaze, R., Muley, A. B., & Jadhav, S. (2024, April 25). In vitro simulated study of macronutrient digestion in complex food using digestive enzyme supplement. Heliyon.
- Rathi, A., Gaonkar, T., Dhar, D. et al. Metabolomics and gut metagenomics profile of the healthy adults on consumption of whey protein supplemented with enzymes-probiotics blend. Discov Appl Sci 6, 147 (2024).
- Rathi A, Gaonkar T, Dhar D, Kallapura G, Jadhav S. Study of amino acids absorption and gut microbiome on consumption of pea protein blended with enzymes-probiotics supplement. Front Nutr. 2024 Jan 23;11:1307734. doi: 10.3389/fnut.2024.1307734. PMID: 38321993; PMCID: PMC10844538.

